{"id":6,"date":"2022-05-17T14:24:38","date_gmt":"2022-05-17T13:24:38","guid":{"rendered":"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/?page_id=2"},"modified":"2024-12-18T11:31:08","modified_gmt":"2024-12-18T11:31:08","slug":"sample-page","status":"publish","type":"page","link":"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/","title":{"rendered":"About"},"content":{"rendered":"\n

Group: Molecular Biology and Mechanisms of Disease<\/h2>\n\n\n\n
\n

Group leader<\/h3>\n\n\n\n
\n
Professor Luminita Paraoan, PhD FARVO FRSB FHEA<\/a><\/div>\n\n\n\n
Get in touch: Luminita.Paraoan@edgehill.ac.uk<\/a><\/div>\n<\/div>\n<\/div>
\"Headshot<\/figure><\/div>\n\n\n\n

Our research<\/h2>\n\n\n\n

Our research aims to further the understanding of fundamental molecular processes and pathways underlying physiology of various eye tissues in health, ageing and degeneration.<\/p>\n\n\n\n

Studying gene expression and regulation in pigmented cells of the eye (retinal pigment epithelial, trabecular meshwork, uveal melanocytes) and focusing on fundamental cellular processes of proteolysis, apoptosis and cellular signalling, the group has identified and characterised key molecular determinants of normal and pathological states of specific eye tissues. The findings have relevance for major eye diseases (age-related macular degeneration, proliferative vitreoretinal disease, uveal melanoma and glaucoma) and wider implications for age-related degenerative processes, proliferative pathology and cancer. Through this we can support progress in their diagnosis and treatment.<\/p>\n\n\n\n

\"Staff<\/figure>
\n

Celebrating Loan’s new paper and Dan’s further manuscript, welcoming Jake and… wishing all our colleagues and collaborators a Merry Christmas!<\/p>\n<\/div><\/div>\n\n\n\n

\n
\n
\"Luminita
Fun on the roof garden with Dr Daniel Grimes, Gunticha Suwanmanee, Dr Ioan Matei, Oliver Maldon and Lauren Blood. June 2023<\/figcaption><\/figure>\n<\/div>\n\n\n\n
\n
\"Luminita
More fun on the roof garden with Dr Daniel Grimes, Gunticha Suwanmanee, Dr Ioan Matei, Oliver Maldon and Lauren Blood. June 2023<\/figcaption><\/figure>\n<\/div>\n<\/div>\n\n\n\n
\"Fun
Fun in the lab with Gunticha Suwanmanee, Dr Dan Grimes, Professor Sirikul Manochantr (visiting from the Centre for Stem Cell Excellence, Thammasat University, Thailand), Dr Ioan Matei and Tanachapa Jantalika. April 2023<\/figcaption><\/figure>\n\n\n\n
\":
Luminita with (r to l) Dr Daniel Grimes, Tanachapa Jantalika, Dr Ioan Matei and Danny Cosgrove \u2013 February 2023<\/figcaption><\/figure>\n\n\n\n
\":
Dr Daniel Grimes with Tanachapa Jantalika (international research fellow) in the new lab. <\/figcaption><\/figure>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Group: Molecular Biology and Mechanisms of Disease Our research Our research aims to further the understanding of fundamental molecular processes and pathways underlying physiology of various eye tissues in health, ageing and degeneration. Studying gene expression and regulation in pigmented cells of the eye (retinal pigment epithelial, trabecular meshwork, uveal melanocytes) and focusing on fundamental […]<\/p>\n","protected":false},"author":2059,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-6","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nMolecular Biology and Mechanisms of Disease | Research<\/title>\n<meta name=\"description\" content=\"Our research aims to further the understanding of fundamental molecular processes and pathways underlying physiology of various eye tissues in health, ageing and degeneration.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Molecular Biology and Mechanisms of Disease | Research\" \/>\n<meta property=\"og:description\" content=\"Our research aims to further the understanding of fundamental molecular processes and pathways underlying physiology of various eye tissues in health, ageing and degeneration.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/\" \/>\n<meta property=\"og:site_name\" content=\"Molecular Biology & Molecular Mechanisms of Disease\" \/>\n<meta property=\"article:modified_time\" content=\"2024-12-18T11:31:08+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/sites.edgehill.ac.uk\/molecular-biology\/files\/2023\/08\/Luminita-Paraoan-1024x1024.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/\",\"url\":\"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/\",\"name\":\"Molecular Biology and Mechanisms of Disease | Research\",\"isPartOf\":{\"@id\":\"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/#primaryimage\"},\"thumbnailUrl\":\"http:\/\/sites.edgehill.ac.uk\/molecular-biology\/wp-content\/uploads\/sites\/336\/2023\/08\/Luminita-Paraoan-1024x1024.jpg\",\"datePublished\":\"2022-05-17T13:24:38+00:00\",\"dateModified\":\"2024-12-18T11:31:08+00:00\",\"description\":\"Our research aims to further the understanding of fundamental molecular processes and pathways underlying physiology of various eye tissues in health, ageing and degeneration.\",\"breadcrumb\":{\"@id\":\"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/#primaryimage\",\"url\":\"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/wp-content\/uploads\/sites\/336\/2023\/08\/Luminita-Paraoan.jpg\",\"contentUrl\":\"https:\/\/sites.edgehill.ac.uk\/molecular-biology\/wp-content\/uploads\/sites\/336\/2023\/08\/Luminita-Paraoan.jpg\",\"width\":1080,\"height\":1080,\"caption\":\"Headshot of Luminita Paraoan. 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